UROP Openings

Have a UROP opening you would like to submit?

Please fill out the form.

Submit your UROP opening

Research-Scale Automated Platform for Optimization of Photochemical Reactions adsa


Term:

Spring

Department:

10: Chemical Engineering

Faculty Supervisor:

Klavs F. Jensen

Faculty email:

kfjensen@mit.edu

Apply by:

01/25/2020

Contact:

Kakasaheb Nandiwale: kakayn@mit.edu

Project Description

Small volume continuous manufacturing is a key platform in pharmaceutical industry due to its small footprint, expanded processing space, and demonstrated benefits from the safety and product quality viewpoints. However, handling solids in flow is still a challenge. At research-scale flow reactors often clog due to solids formation when screening a wide range of conditions. The overall goal of the project is to design and develop state-of-the-art automated platform able to handle slurries/solids formed during a chemical transformation to achieve a robust reaction optimization. The proposed platform is based on a mini CSTR (Continuous-Stirred-Tank-Reactor) cascade approach. The constructed platform will be tested using organic/photochemical reactions involving solids/slurries. During this project, UROP students will have an opportunity to learn about automated optimization system, online analysis, and integration of software and hardware.

Pre-requisites

Student with some programming (MATLAB, Python, LabVIEW) and organic chemistry knowledge are welcome to apply.